Sai Wen

Email: wensai@btbu.edu.cn

Position

Associate Professor, Ph.D.

Associate Director, Department of Bioengineering, Beijing Technology and Business University

Education Background

2003.09-2007.06 Beijing University of Chemical Technology, Bacholar degree in Bioengineering, Beijing, PR. China

2007.06-2012.12 Beijing University of Chemical Technology, PhD in Biochemical Engineering, Beijing, PR. China.

2010.10-2011.11 University of Illinois at Urbana-Champaign, Joint PhD student in chemistry and molecular biology, Illinois, USA

Research Field/Interests

1. Biosynthesis Technology: Directed evolution and rational design of novel enzymes; Construction of cell factories for chemicals and peptides; Microbial fermentation and process optimization.

2. Food Biotechnology: Development and comprehensive utilization of antibacterial proteins/peptides and functional oligopeptides for food industry.

Research Grants

1. The National Natural Science Fund (No. 21406005).

2. Support Project of High-level Teachers in Beijing Municipal Universities in the Period of 13th Five–year Plan (No. CIT&TCD201904040).

3. Scientific Research Starting Foundation for Young Talents in Beijing Technology and Business University (No. QNJJ2014-28)

Publications

1. Sai Wen, Tongxin Mao, Dongmei Yao, Tian Li, and Fenghuan Wang, Yeast Surface display of Antheraea pernyi lysozyme revealed α-helical antibacterial peptides in its N-terminal domain，Journal of Agricultural and Food Chemistry (SCI), 2018, 66, 9138−9146.

2. Sai Wen, Jianguo Yang, Tianwei Tan. Full-length single-stranded PCR product mediated chromosomal integration in intact Bacillus subtilis. Journal of Microbiological Methods (SCI). 92: 273-277, 2013.

3. Sai Wen, Tianwei Tan, Huimin Zhao. Improving the Thermostability of Lipase Lip2 from Yarrowia lipolytica. Journal of Biotechnology (SCI). 164: 248-253, 2012.

4. Sai Wen, Tianwei Tan, Mingrui Yu. Immobilized lipase YlLip2-catalyzed resolution of (±) α-phenylethyl amine in a medium with organic cosolvent. Process Biochemistry (SCI).43:1259-1264, 2008.

5.Mingrui Yu, Sai Wen, Tianwei Tan. Enhancing production of Yarrowia lipolytica lipase Lip2 in Pichia pastoris. Engineering in Life Sciences (SCI). 10: 458-464, 2010.

Teaching Interests

Compulsory undergraduate courses: Biochemistry, Genetic engineering, etc.

Compulsory postgraduate courses: Scientific English, Biorefinery processes and products, etc.